If total cholesterol is between 200 to 239mg/dl and HDL is 40mg/dl or more, one would need to determine, through their doctors, if they have other risk factors for heart disease. A lipoprotein profile may be necessary in this case.If your total cholesterol 240mg/dl or above, regardless of HDL cholesterol, one would need a lipoprotein profile done. If the LDL cholesterol less than 130mg/dl, one would only need to have their cholesterol levels tested in the next five years, because they are in the desired range. If LDL 130mg/dl or above, one would need to have their physician evaluate any other cardiovascular disease risk factors as possible.