Some evidences links a scarcity of folate with the depression. Evidence limited of randomized showed with acid folic, beyond antidepressants, especially SSRIs, can have benefits. Research of the University of York and Hull Medical York School discovered a linking between depression and basses folate levels. A study carried through for the same involved team 15,315 individuals. However, the evidence is probably very limited at this moment so that this is a recommendation of treatment of routine. Supplementation of acid folic affects receiving noradrenalin and serotonin in the brain that could be the possible cause of the capacity of the acid folic to act as an antidepressant.
Memory and mental agility
In a judgment of three years in 818 people with age above of 50, memory of short term, mental agility, and verbal fluency had been found to be better between that they had taken 800 micrograms of acid folic per day, the double of the current RDA, what those that had taken placebo.
Schizophrenia
The folate deficiency can increase the risk of schizophrenia, because, when increasing the levels of homocysteine, folate also increases the interleukin the 6 and levels of alpha tumor necrosis of the factor, and these two cytosine is involved in the development of the schizophrenia. The involved accurate mechanisms in the development of the schizophrenia are not total clear, but it can have something to see with the mutilation of the DNA and a carbon metabolism, and these are the specific papers of acid folic in the organism.
The allergic illnesses
Exist a relation between the acid folic and allergic illnesses. In a study that it examined the relation enters the siroccos levels of folate and of utopia markers; sibilance and asthma in 8.083 individuals, the levels of sirocco folate had been found to be inversely proportional to the level of IgE, utopia and sibilance in a relation dose-reply. Increase of the folate levels had also been associates to the reduction of the risk of asthma diagnoses for doctor. Supplementation of acid folic during the delayed pregnancy is associated with an increased risk of asthma in infancy, greater risk of persistent asthma and worsening of the respiratory function in small children.
The attrite rheumatoid
The acid folic in the dose of 5-27 mg per week is used to protect the patients with attrite rheumatoid that they are to take methotrexate of the toxic effect of the drug.